Harley Quinn (KALEY CUOCO) has finally broken things off once and for all with the Joker (ALAN TUDYK) and attempts to make it on her own as the criminal Queenpin of Gotham City in this half-hour adult animated action-comedy series. With the help of Poison Ivy (LAKE BELL) and a ragtag crew of DC castoffs, Harley tries to earn a seat at the biggest table in villainy: the Legion of Doom!