Jackie Kallen isn't fighting for glory. She's fighting for respect. Inspired by a true story, Against The Ropes stars Meg Ryan as Kallen, a sassy, brassy boxing manager-in-the-making determined to change "Lethal" Luther Shaw (Omar Epps) from a mere street punk into a world-class prizefighter. To help Shaw rise to the rank of number-one contender, Jackie coaxes veteran trainer Felix Reynolds (Charles S. Dutton) out of retirement. But before they can all realize their dream of a championship bout, they must first learn what it takes to stand in each other's corner. It's not about how you fall. It's about how hard you fight back when you are Against the Ropes.