The Eric Andre Show takes the elements of a traditional late night talk show and ruins them. Likely the world's most inept and violent host, Eric Andre interviews A-List talent like Russell Brand, Fergie and Jerry Seinfeld with the help of co-host Hannibal Buress. However, no celebrity of sound mind would ever do this show, necessitating Eric's comedian friends and local weirdoes to fill in as pretend, budget versions of stars. Eric asks these celebrities the questions you wish Leno had the gall to ask and gets the answers you wish they'd actually give. Interviews are broken up with assorted man-on-the-street segments, surreal flashes of inexplicable studio chaos and the general deconstruction of late night's most beloved tropes.