To pass a college initiation, five medical school students - Devon (Melanie Lewis), Elizabeth (Yolanda Pecoraro), Ashley (Kristin Novak), Tori (Annie Burgstede) and Heather (Steffany Huckaby) - are dared to spend the night in the Waverly Hills Sanatorium, an abandoned mental institution where over 60,000 people died of the white plague. Discovering they share a connection to the building's horrific past, the students encounter five ghosts who haunt the hospital. When supernatural forces kill four of the girls, the sole survivor attempts to escape through the death tunnel, a 500-foot underground passage through which the plague victims were carried to their final resting place.