This thrilling sequel to The Fly follows Francois and Philippe Delambre, brother and son of Andre Delambre, who died as a result of his experiments with a matter-transmitting device. It is now 12 years later and Phillipe has just laid his mother to rest. Having watched his mother live out her final days traumatized, he vows to perfect the matter transmitter. But when Phillipe enlists the help of a man who conspires to steal the secret of the device, Philippe falls victim to the same disaster that befell his father: his body parts are transposed with those of a house-fly.