Pilot
Season 1, Episode 1 TV-14
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It's a matter of life or death. When a new patient is in desperate need of a heart transplant, we are introduced to the life of world renowned heart transplant surgeon Dr. Alexandra Panttiere (Melissa George). There is nothing conventional about Alex. She is as cutting edge and unorthodox in the OR as she is with the two men in her life. Her approach to medicine is without boundaries, as is her approach to everything else in her world, which is always full of surprises.
Twins
Season 1, Episode 2 TV-14
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When conjoined twins arrive at the hospital with a cancer diagnoses, Alex recommends a very risky surgery, resulting in a major ethical debate within the department. After spending time with the twins and observing their unique relationship, Alex also begins to question her relationship with Pierce.
Backwards
Season 1, Episode 3 TV-14
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When a young man is only able to speak sentences backwards, Alex (Melissa George) sees this as the perfect opportunity to test out some new technology. While Jesse (Don Hany) agrees this is the best course of action, Millicent (Shelley Conn) believes otherwise. This tension within their department might stem from past history which could further complicate things between Alex and Pierce (Dave Annable). Jamie Kennedy, D.L. Hughley, Maya Erskine, Joshua Leonard and JLouis Mills also star.
100,000 Heartbeats
Season 1, Episode 4 TV-14
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Alex (Melissa George) and Pierce (Dave Annable) disagree on whether an experimental treatment for those with advanced stage cancer is right for the hospital's patients. True to form, Alex takes matters into her own hands with a risky move to find volunteers. Meanwhile, Max (Joshua Leonard) looks to drastically change the family dynamic with Alex, and Ji-Sung (Maya Erskine) connects with Callahan (Jamie Kennedy).
The Land of Normal
Season 1, Episode 5 TV-14
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On the anniversary of her sister's death, Alex (Melissa George) performs state of the art heart surgery on a patient who doubts her ability to leave personal grief outside the OR. Meanwhile, Millicent (Shelley Conn) dates a sexy artist, and Pierce (Dave Annable) wants to be a bigger part of Alex's family.
The Inverse
Season 1, Episode 6 TV-14
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A case brings back memories for Alex (Melissa George), Jesse (Don Hany) and Millicent (Shelley Conn) as they fight to save a heart transplant patient when she sustains devastating injuries in a car crash. Also starring Dave Annable, Maya Erskine and Jamie Kennedy. Guest starring Rudy Martinez, Caitlyn Larimore, Sara Tomko, Makenzie Vega, Stephanie Nash and Rubén Garfias.
Permanent Glitter
Season 1, Episode 7 TV-14
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When a transgender woman is diagnosed with breast cancer, Alex (Melissa George) and Ji-Sung (Maya Erskine) fight to save her life and her identity. Meanwhile, a beautiful consultant from another hospital forces Jesse (Don Hany) to confront his feelings for Alex. Also starring Dave Annable, Shelley Conn, Joshua Leonard and D.L. Hughley. Guest starring Candis Cayne, Brianne Davis, Andrew T. Lee, Caitlyn Larimore, Rudy Martinez, and Megan McNulty.
Match Game
Season 1, Episode 8 TV-14
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When Alex's (Melissa George) father needs a new kidney, an unlikely donor emerges and family secrets threaten to destroy the close relationship between father and daughter. Also starring Dave Annable, Don Hany, Shelley Conn, Jamie Kennedy, D.L. Hughley, Maya Erskine and JLouis Mills. Guest starring Michael Nouri, JoBeth Williams, Brenda Bakke, Rudy Martinez and Gracie Grenier.
Sanctuary
Season 1, Episode 9 TV-14
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Alex (Melissa George) and Jesse (Don Hany) put the hospital's reputation on the line while trying to fulfill the dying wish of a young heart patient. Also starring Dave Annable, Shelley Conn, Joshua Leonard, Jamie Kennedy, D.L. Hughley, Maya Erskine and JLouis Mills. Guest starring Rusty Schwimmer, James Hiroyuki Liao, Andy Walken, Caitlyn Larimore and Rudy Martinez.
What Happens in Vegas...Happens
Season 1, Episode 10 TV-14
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In the season finale of "Heartbeat," Alex (Melissa George) fights to save the lives of Jesse (Don Hany), Pierce (Dave Annable) and Ji-Sung (Maya Erskine) when a mysterious and deadly illness sends the hospital into lockdown. Meanwhile, Millicent must pick up the pieces when Alex disobeys the orders of the CDC, and an elderly man searching for his missing wife leads Alex to make a drastic decision in her love life. Also starring Joshua Leonard and Jamie Kennedy. Guest starring Kevin Weisman, Mo Gaffney, Sara Paxton, Caitlyn Larimore, Rudy Martinez and Lenora May.
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