As CSI enters its 12th season, the team is still recovering from the fallout from the Nate Haskell case several months after its completion. Ray Langston has been let go and a new CSI supervisor, D.B. Russell, played by Ted Danson, has been hired. The Las Vegas crime lab also welcomes another new addition, a young CSI from Los Angeles and Ecklie's estranged daughter, Morgan Brady. The team must build new relationships as they solve cases that include a multiple homicide on a Vegas tram and a "Strangers on a Train" type case where numerous suspects who seem to be unrelated confess to murdering a family.