After living with and learning from her amnesia, Samantha Newly has been given a new lease on life. In Season two, Sam will grow into her own person, both for better and for worse, and her transformation will inspire surprising changes in her friends and family. Every life has its ups and downs, but if you can find out what – and who – really matters in your life, you’ll do just fine. Christina Applegate leads a stellar cast in this unforgettable hit comedy that proves it’s never too late to become the person you should have always been.