It's been two years since the guys prowled the seamy side of Las Vegas in a roofie haze and recovered from being kidnapped, shot at and chased by drug-dealing mobsters in Bangkok. Phil, Stu and Doug are happily living uneventful lives at home -- tattoos have been lasered off, files purged. And the last they heard from disaster-magnet Leslie Chow, he'd been tossed into a Thai prison. The only member of the Wolfpack who's not content is Alan. Still lacking a sense of purpose, the group's black sheep has ditched his meds and given in to his natural impulses in a big way -- which, for Alan, means no boundaries, no filters and no judgment -- until a personal crisis forces him to finally seek the help he needs. And who better than his three best friends to make sure he takes the first step. This time, there's no bachelor party. No wedding. What could possibly go wrong? But when the Wolfpack hits the road, all bets are off.