FaST-LMM-Select for addressing confounding from spatial structure and rare variants
- Jennifer Listgarten ,
- Christoph Lippert ,
- David Heckerman
MSR-TR-2013-137 |
Second International Enterprise Distributed Object Computing Workshop (EDOC )
A recent report by Mathieson and McVean showed that confounding in genome-wide association studies (GWAS) resulting from spatially structured populations in conjunction with rare variants could not be corrected by currently available statistical genetics methods.