Ambushed at their isolated home by Sheriff Wydell (William Forsythe) and a squad of armed men, the Firefly family wakes up one morning with guns blazing - yet only Otis (Bill Moseley) and his sister, Baby (Sheri Moon Zombie), manage to escape the barrage of bullets unharmed. Hiding out in a backwater motel, the wanted siblings wait to rendez-vous with their errant father, Captain Spaulding (Sid Haig), killing whoever happens to stand in their way.