The repercussions from the Money Train Heist continue to plague the Mackey family as Vic ignites a war between the Armenian mob and a powerful drug cartel with ties to the Mexican government. In a plan to punish Shane for Lem's death, he tries playing all sides from the middle as he partners with a Latino real estate baron who, with help from a compromised federal agent, is blackmailing mayoral candidate David Aceveda. As a convicted murderer looks for a deal by threatening to expose Claudette's medical history, and Dutch tries to stop a teenager from growing up to be a serial killer, Vic's revenge scheme forces the increasingly desperate Shane and his family to go on the run. And after leveraging a confession into a guarantee of immunity for the Strike Team's crimes and a job with a federal task force, Vic is sent careening toward twin showdowns with Shane and the Mexican cartel.